METHOD FOR MAKING LOW-MOLECULAR HEPARIN Russian patent published in 2010 - IPC A61K31/727 C08B37/10 

Abstract RU 2377993 C2

FIELD: medicine.

SUBSTANCE: invention concerns medicine, more exactly to drug technology intended for treatment of thrombotic conditions. There is offered method for making low-molecular heparin with using enzyme depolymerisation, characterised by adding dry lysozyme to 1% heparin in 0.1 M NaCl in the weight relation 1:100, mixing at 50°C within 3 hours, desalting with sephadex column and lyophilised.

EFFECT: invention ensures production of low-molecular heparin with using ovalbumin lysozyme enzyme.

3 ex, 2 tbl

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RU 2 377 993 C2

Authors

Bannikova Galina Evgen'Evna

Drozd Natal'Ja Nikolaevna

Varlamov Valerij Petrovich

Makarov Vladimir Aleksandrovich

Tolstenkov Aleksandr Sergeevich

Lapikova Elena Sergeevna

Miftakhova Nadzhija Tairovna

Il'Ina Alla Viktorovna

Lopatin Sergej Aleksandrovich

Skrjabin Konstantin Georgievich

Dates

2010-01-10Published

2007-11-08Filed