FIELD: medicine.
SUBSTANCE: in biopsy samples of lung tissue evaluated is proliferative activity of cells of connective tissue by immunohystochemical method determining proliferation index by means of regulatory protein Ki-67. If in analysed sample proliferation index does not exceed 1%, first stage of pleural empyema is diagnosed. If proliferation index of analysed sample in zone of inflammatory changes is higher than 17% and in zone of lung with visually preserved structure it is from 5% to 12%, II stage of pleural empyema is diagnosed, if proliferation index in zone of inflammatory changes is higher than 17% and in zone of lung with visually preserved structure it is higher than 12%, III stage of pleural empyema is diagnosed.
EFFECT: increased accuracy of pleural empyema stage diagnostics.
3 ex
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