FIELD: chemistry.
SUBSTANCE: invention relates to novel compounds of formula I 
, in which A denotes hydrogen, B denotes methyl or B is in a trans-position relative oxygen; X denotes CH2; Y denotes a group of formula 
, 
, 
,
, 
or 
;
, in which the left-hand bond is to an oxygen atom, and the right-hand bond is to the group R; R denotes 5-indolyl; in form of a free base or an acid addition salt. The invention also relates to a pharmaceutical composition, to use of compounds in any of claims 1-7, to a method of preventing and treating psychiatric and neurodegenerative disorders in a person, as well as a method of treating and preventing diseases or pathological condition in which α7 nAChR activation plays a role.
EFFECT: obtaining novel biologically active compounds having α7 nAChR agonist activity.
16 cl, 4 ex
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