AZABICYCLIC ALKANE DERIVATIVES SUBSTITUTED WITH CONDENSED BICYCLOHETEROCYCLE Russian patent published in 2011 - IPC C07D451/08 C07D451/14 A61P25/00 A61K31/4375 

FIELD: chemistry.

SUBSTANCE: invention relates to azabicyclic alkane derivatives which are substituted with a condensed bicycloheterocycle of formula or pharmaceutically acceptable salt thereof, ester, amide or prodrug, where n equals 1, 2 or 3; A denotes N or N⁺-O^-; R denotes hydrogen, alkyl, cycloalkylalkyl and arylalkyl; L is selected from a group consisting of O, S and -N(R_a)-; Ar¹ denotes a 6-member aryl or a 6-member heteroaryl; and Ar² denotes a bicyclic heteroaryl; and R_a is selected from a group consisting of hydrogen, alkyl and alkylcarbonyl; provided that if Ar¹ is represented by formula then L denotes O or S; compositions containing such compounds, and methods of treating conditions and disorders using said compounds and compositions.

EFFECT: improved properties of the derivatives.

19 cl, 66 ex