INACTIVATED COMBINED VACCINE AGAINST INFECTIOUS RHINOTRACHEITIS, PARAFLU-3, RESPIRATORY SYNCYTIAL DISEASE, VIRAL DIARRHEA AND PASTEURELLOSIS OF CATTLE Russian patent published in 2010 - IPC A61K39/295 A61P31/00 

FIELD: medicine, veterinary.

SUBSTANCE: invention relates to field of veterinary microbiology. As active substance vaccine contains mixture of inactivated virus suspension of strain of virus of infectious rhynotracheitis of cattle, SCV No 2333, of family Herpesviridae, subfamily Alphaherpesviridae, inactivated virus suspension of strain of virus of cattle paraflu-3 SCV No 2334 subfamily Paramixovirinae, genus Paramixovirus, inactivated virus suspension of strain of virus of cattle respiratory syncytial disease SCV No 2335, subfamily Pneumoviridae, genus Pneumovirus, inactivated virus suspension of strain of virus of cattle diarrhea SCV No 2336, family Flaviviridae, genus Pestivirus, with activity of each virus strain being not less than 10^6.5 TCD₅₀ in 1 cm³ of vaccine, and inactivated suspension of cells of bacteria Pasteurella multocida serovar A strain 1231, inactivated suspension of cells of bacterium Pasteurella multocida serovar B strain 656, inactivated suspension of cells of bacterium Pasteurella multocida serovar D strain T-80, inactivated suspension of cells of bacterium Mannheimia haemolytica strain 169, in efficient quantity, taken in mixture in equal proportion with concentration not less than 3 billion microbial cells in vaccine dose.

EFFECT: vaccine possesses high specificity, stability in preservation of biological properties, creates expressed immunity, is harmless.

3 cl, 10 tbl, 6 ex