METHOD OF MEASURING RESISTANCE AND SENSITIVITY TO DOCETAXEL Russian patent published in 2010 - IPC G01N33/50 C12Q1/68 G01N33/68 

Abstract RU 2403574 C2

FIELD: medicine.

SUBSTANCE: essence of invention includes selection of sample for testing from area of malignant affection in patient, suffering from cancer of large intestine, selection of control sample, measurement of the level of one or several genetic markers, selected from the group, comparison of measured levels in experimental samples with control ones. Reducing of levels of one or several genetic markers in comparison with control sample, indicates increased resistance to docetaxel. Also described are sets which allow to predict or realise monitoring of patient's response to docetaxel.

EFFECT: identification of genetic markers, by which it is possible to realise patient's response to chemical therapy by docetaxel.

18 cl, 9 ex, 3 tbl, 16 dwg

Similar patents RU2403574C2

Title Year Author Number
TREATMENT OF SIRTUIN (SIRT) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO SIRTUIN (SIRT) 2011
  • Kollard Dzhozef
  • Khorkova Sherman Olga
  • Kojto Karlos
  • De Leon Belinda
RU2693462C2
MODIFIED NATURAL KILLER CELLS AND NATURAL KILLER CELL LINES WITH INCREASED CYTOTOXICITY 2016
  • O`Dvajer, Majkl Imon Piter
RU2772348C2
CELL THERAPY BASED ON IMPROVED NATURAL KILLER CELLS 2017
  • O Dvajer, Majkl Imon Piter
  • Khu, Dzhinson
RU2776890C2
NOVEL PEPTIDES AND PEPTIDE COMBINATIONS FOR USE IN IMMUNOTHERAPY OF LUNG CANCER, INCLUDING NON-SMALL CELL LUNG CANCER (NSCLC) AND OTHER CANCERS 2016
  • Mahr, Andrea
  • Weinschenk, Toni
  • Schoor, Oliver
  • Fritsche, Jens
  • Singh, Harpreet
  • Wagner, Claudia
  • Leibold, Julia
  • Song, Colette
RU2723092C2
CELL BASED QUALITY CONTROL BIOASSAYS FOR NUTRICEUTICAL AND MEDICINAL PRODUCTS 2013
  • Khalperin Zhoze A.
  • Chorev Majkl
  • Aktas Khusejn
RU2662358C2
POLYPEPTIDES AND POLYNUCLEOTIDES AND THEIR USE FOR TREATMENT OF IMMUNE DISORDERS AND CANCER 2012
  • Toporik Amir
  • Novik Amit
  • Shemesh Ronen
RU2623161C2
3'-UTR SEQUENCES FOR RNA STABILIZATION 2016
  • Orlandini Fon Nissen, Aleksandra
  • Fesser, Shtefani
  • Vallatstsa, Britta
  • Bajssert, Tim
  • Kun, Andreas
  • Zakhin, Ugur
  • Poleganov, Marko Aleksandr
RU2783165C1
PHOSPHODIESTERASE 9A AS MARKER OF MALIGNANT TUMOR OF PROSTATE GLAND 2010
  • Khoffmann Ralf
  • Khauslej Majlz D.
  • Khenderson Devid Dzh. P.
RU2592668C2
METHODS FOR PREDICTING PROSTATE CANCER 2016
  • Hoffmann, Ralf
  • Den Biezen-Timmermans, Eveline
  • Van Strijp, Dianne Arnoldina Margaretha Wilhelmina
  • Van Brussel, Anne Godefrida Catharina
  • Alves De Inda, Marcia
  • Wrobel, Janneke
  • Van Zon, Joannes, Baptist, Adrianus, Dionisius
RU2760577C2
T-CELL COMPOSITIONS WITH T-CELL RECEPTOR DEFICIENCY 2013
  • Sentman, Charles, L.
RU2781979C2

RU 2 403 574 C2

Authors

Grjuneberg Dorre

Khuan Si

Natesan Sridaran

Ogast Pol

Dates

2010-11-10Published

2005-12-01Filed