CLAY PIPE CANCER THERAPY Russian patent published in 2010 - IPC A61M1/38 A61K31/196 A61K31/513 A61P35/00 A61B17/00 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to oncology, and can be used within integrated treatment of locally advanced clay pipe cancer. That is ensured by blood sampling in the amount 200-250 ml from the median cubital vein, centrifugation and plasma separation in the amount 10 ml in 9 syringes of 20 ml. Plasma containers are placed in a freezing chamber, and the rest cell suspension is added with 150 ml of physiologic saline and reinfused intravenously drop-by-drop. On the following day, the lingual artery is catheterised to introduce a mixture incubated at temperature 37 C for 30 minutes and containing 10 ml of autoplasma and 30 mg of methotrexate in one syringe and 500 mg of 5-fluorouracil and 10 ml of autoplasma in the second syringe. Such mixture is introduced daily during 4 days. 3 weeks later, a surgical removal the tumour follows with a bed of the removed tumour being injected all around during the operation with the mixture of 30 mg methotrexate and 10 ml of autoplasma incubated similarly that is followed with operative wound closure.

EFFECT: method allows higher clinical effectiveness in the case patients that is ensured by chemopreparations depot in a tumour lesion.

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