METHOD OF COMBINATION THERAPY OF CIRCUMSCRIBED SCLERODERMIA WITH APPLYING LOCAL TRANSDERMAL ENZYMIC ELECTROSTATIC EXPOSURE Russian patent published in 2010 - IPC A61N1/30 A61M35/00 A61K31/43 A61K38/43 A61P17/00 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, particularly - to dermatology. It involves hospital treatment by the intramuscular introduction of penicillin, lydase, unitiol. Penicillin is introduced in dosage 400 thousand units, 3 times a day, in the course 14-18 million units. Lydase is introduced in dosage 64 UN daily, in the course 15-20 injections. 5% unitiol is introduced in amount 2 ml, every second day, in the course 10 injections. In addition, plaques are treated by the applications of electrostatic films. The films are applied on pads impregnated with ronidase solution in dosage 0.5 g in 30 ml of acetate buffer solution. The films are left for 3 - 4 days. And then they are changed. Total application time is 12 - 14 days. 1.5 - 2 months later, similar applications of 0.5% trypsin or chemotrypsin are performed in the outpatient setting.

EFFECT: method eliminates possible enlargement of circumscribed damage regions and process extension to the other skin areas.

2 ex, 2 cl