VACCINE AGAINST COLIBACTERIOSIS OF RABBITS Russian patent published in 2010 - IPC A61K39/108 A61P31/04 

FIELD: medicine, veterinary science.

SUBSTANCE: invention relates to the field of veterinary science. Vaccine as antigen contains suspension of cells of pure culture of causative agent Escherichia coli 035, produced by picking affected organs from fallen rabbits from local epizootic focus, preparation of suspension, inoculation in differential-diagnostic media, extraction of pure culture of causative agent and growth in meat-peptone broth until concentration of microbial cells makes 5-6 billion in 1 cm³, formalin and alumnium hydroxide at the following ratio of components, wt %: suspension of cells of pure culture of causative agent Escherichia coli 035 in meat-peptone broth with titre of 5-6 billion microbial cells in 1 cm³ - 83.0-85.5, formalin - 1.0-2.0, aluminium hydroxide - balance.

EFFECT: produced vaccine is harmless, highly immunogenic, specific, stable in storage.

1 tbl, 5 ex