FIELD: medicine.
SUBSTANCE: invention refers to recombinant insect defensin expression in a cell of filamentous fungi Aspergillus. The given cell is transformed by a genetic maker coding insect defensin, and contains one or more intron sequences. The intron sequence can be enclosed in any maker segment of nucleic acid.
EFFECT: application of the offered maker makes the level of recombinant defensin expression to be improved as compared to application of a nucleic acid maker without intron sequences.
6 cl, 1 tbl, 6 ex
| Title | Year | Author | Number |
|---|---|---|---|
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|
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| POLYPEPTIDES HAVING ANTIMICROBIAL ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME | 2006 |
|
RU2512525C2 |
| POLYPEPTIDE WITH PHOSPHOLIPASE ACTIVITY AND USE THEREOF | 2004 |
|
RU2363731C2 |
| ENZYME PROTEASE AND ITS APPLICATION | 2012 |
|
RU2611043C2 |
| FILAMENTOUS FUNGI HAVING ALTERED VISCOSITY PHENOTYPE | 2011 |
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RU2608639C2 |
