ANTENNA-APPLICATOR AND DEVICE FOR DETERMINING TEMPERATURE CHANGES OF INTERNAL TISSUES OF BIOLOGICAL OBJECT AND METHODS OF DETERMINING TEMPERATURE CHANGES AND CANCER RISK DETECTION Russian patent published in 2010 - IPC A61B5/01 A61N5/02 G01N22/00 G01K13/00 

FIELD: medicine.

SUBSTANCE: invention relates to field of medicine, namely to devices and methods for determining temperature changes in internal tissues of biological object and can be used for non-invasive early detection of cancer risk. Antenna-applicator contains segment of wave guide, partly or completely filled with dielectric, which has one closed end and opposite open end, contacting with biological object, system of electromagnetic waves excitation, located in wave guide between closed end of wave guide and dielectric, connected with inlet part of microwave radiothermometre and sensor of skin temperature, located near open end of wave guide, made with possibility to transmit information to computing device. Device for determining temperature changes in addition to antenna-applicator includes microwave radiothermometre, measuring intensity of signal, coming from antenna outlet, proportional to brightness temperature of biological object tissues, and computing device, made with possibility to receive information from sensor of skin temperature and from microwave radiothermometre and to detect changes in temperature of internal tissues. Also claimed are method of determining changes of internal tissues and method of determining changes of internal tissues in time, by simultaneous measurement of brightness temperature and skin temperature in the first and the second points, at the first and at the second moments of time, taking into account coefficient of skin temperature contribution to brightness temperature. Also claimed are methods of detecting high risk of cancer in biological object, in particular of breast cancer, by simultaneous measurement of brightness temperature and skin temperature in the reference and specified points of biological object, determination of tissue thermal activity level, on the basis of which parametre W, characterising cancer risk, is determined, and determination of cancer risk by comparison of parametre W with threshold level of cancer risk.

EFFECT: application of invention allows to detect temperature changes in internal tissues, simplifies measurement process and increases method sensitivity in detection of cancer risk.

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