WATER-BASED HFSH COMPOSITIONS Russian patent published in 2010 - IPC A61K9/08 A61K38/24 A61K31/195 

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to medicine and pharmacology, and represents a water-based composition of human follicle-stimulating hormone (HFSH) containing a therapeutically effective amount of the HFSH and glycine, methionine, a nonionic surface active agent and a phosphate buffer as stabilisers, and the amount of glycine is 0.1 to 10% (wt/vl), the amount of methionine is 0.01 to 2.0 % (wt/vl), the amount of the nonionic surface active agent is 0.001 to 0.02% (wt/vl), and the nonionic surface active agent is specified in a group consisting of a polysorbate nonionic surface active agent, a poloxamer nonionic surface active agent or combinations of those, and the phosphate buffer has salt concentration 1mM to 50 mM and pH 6.5 to 7.5.

EFFECT: invention provides maintained long-term HFSH stability.

5 cl, 4 ex, 7 tbl