FIELD: medicine, pharmaceutics.
SUBSTANCE: group of inventions refers to pharmaceutics and concerns a water-based formulation of a follicle-stimulating hormone (hFSH) for treating sterility, containing one or more stabilising agents, L-methionine, Polysorbate 20, phosphate buffer providing pH within the range of 6.5 to 8, water for injections; it additionally contains sodium chloride as a thermally stable agent, and also concerns using sodium chloride as the thermally stable agent in the water-based formulation of hFSH.
EFFECT: group of inventions provides the stability of the water-based formulation of hFSH for a long period of time, and prevents dissociations of alpha- and beta- subunits of human FSH.
9 cl, 5 dwg, 3 tbl, 4 ex
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