INJECTABLE DEPOT FORMULATIONS AND METHODS FOR PROVIDING PROLONGED RELEASE OF NANOPARTICLE COMPOSITIONS Russian patent published in 2010 - IPC A61K31/496 A61K31/425 A61K47/00 A61K9/08 A61K9/14 B82B1/00 B82B3/00 A61P25/18 

FIELD: medicine, pharmaceutics.

SUBSTANCE: there are described injectable pharmaceutical depot formulations containing a free base of ziprasidone or its pharmaceutically acceptable salt, pharmaceutically acceptable carrier, and preferentially at least two surface stabilisers. Said compound of ziprasidone is presented in the form of nanoparticles of mean particle size less than approximately 2000 nm.

EFFECT: invention provides maintained effective mean particle size of the compound of ziprasidone, and sterilisation and storage stability of the formulation.

22 cl, 19 ex