ANTIVIRAL ACTIVE COMPONENT, PHARMACEUTICAL COMPOSITION, MEDICINAL AGENT, METHOD OF TREATING VIRAL DISEASES Russian patent published in 2010 - IPC C07D235/14 C07D401/06 C07D403/06 C07D403/12 C07D405/06 A61K31/454 A61K31/4178 A61K31/496 A61K31/5355 A61P31/12 

FIELD: chemistry.

SUBSTANCE: invention relates to novel antiviral active components which are substituted 2-aminomethyl-1-benzyl-1H-benzo[d]imidazoles of general formula 1 or pharmaceutically acceptable salts thereof, a pharmaceutical composition, antiviral medicinal agents, a method of preventing and treating viral diseases, especially those cause by hepatitis C virus (HCV). In general formula 1

, R¹ denotes one or two substitutes of a cyclic system, including a hydrogen atom, C₁-C₃ alkyl, C₁-C₃ alkyloxy or a halogen atom; R² denotes a hydrogen atom or C₁-C₃ alkyl; R³ and R⁴ denote identical substitutes of amine groups, including hydrogen, C₁-C₂ alkyl, C₁-C₃-alkanoy, optionally substituted furanoyl; optionally substituted or optionally annelated with a 5-6-member azaheterocyclic ring of phenyl; or R³ and R⁴ together with a nitrogen atom with which they are bonded form a morpholin4-yl, 4- (C₁-C₃ alkylsubstituted)-piperazin-1-yl, and R¹ and R² assume values given above, or piperidin-1-yl, provided that R¹ assumes the value given above, R² denotes C₁-C₃ alkyl, or provided that R¹ denotes hydrogen or o-fluorine, R² assumes the value given above.

EFFECT: improved method.

7 cl, 1 tbl, 4 ex