PHARMACEUTICAL COMPOSITION CONTAINING DOCETAXEL AND DEGRADATION INHIBITOR AND METHOD FOR PREPARING THEREOF Russian patent published in 2011 - IPC A61K9/08 A61K31/337 A61K47/12 A61K47/14 

Abstract RU 2408362 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to medicine, namely a pharmaceutical composition containing Polysorbate 80, anhydrous docetaxel (I) or its trihydrate and organic acid used as a degradation inhibitor and characterised by pH value within 2.5-4.5.

EFFECT: pharmaceutical compositions of at least 30 months of storage at room temperature understood as temperature within the range 15-30°C±1°C, provide sterility and stability, as well as low concentration of 7-epi-docetaxel(II).

13 cl, 2 tbl, 6 ex

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RU 2 408 362 C2

Authors

Machado Antonio

Maranduba Aurelio

Guimaraes Eneida

Machado Livia

Santiago Dzhunior Martsio

Silva Maria

Dates

2011-01-10Published

2006-02-09Filed