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2 408 579

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IPC

C07D209/12(2006-01-01)

C07D403/06(2006-01-01)

A61K31/404(2006-01-01)

A61P9/06(2006-01-01)

A61P23/02(2006-01-01)

(21) (22)

Application

2008153020/04, 2008-12-31

(24)

Start date

2008-12-31

(22)

Actual filing date

2008-12-31

(45)

Published

2011-01-10

(72)

Inventor

Suzdalev Konstantin FilippovichBabakova Marija NikolaevnaGalenko-Jaroshevskij Pavel AleksandrovichVarlashkina Inessa AleksandrovnaCherednik Irina LeonidovnaShejkh-Zade Jurij ReshadovichTaran Oksana Anatol'EvnaTakhchidi Khristo PeriklovichSakhnov Sergej NikolaevichDol'Skaja Oksana AleksandrovnaLisitsyna Nadezhda PavlovnaBguasheva Behlla AskerovnaBogus Saida Kazbekovna

(73)

Holder

Federal'Noe Gosudarstvennoe Obrazovatel'Noe Uchrezhdenie Vysshego Professional'Nogo Obrazovanija Federal'Nyj Universitet"Gosudarstvennoe Obrazovatel'Noe Uchrezhdenie Vysshego Professional'Nogo Obrazovanija Gosudarstvennyj Meditsinskij Universitet Federal'Nogo Agentstva Po Zdravookhraneniju I Sotsial'Nomu Razvitiju",

HYDROGEN HALIDES OF N-[2-(1ALKYL-1H-INDOL-3-LY)-1-(4-ALKYLPIPERAZINE-1-CARBONYL)-VINYL]-2-FLUOROBENZAMIDE, HAVING LOCAL ANAESTHETIC AND ANTIARHYTHMIC ACTIVITY Russian patent published in 2011 - IPC C07D209/12 C07D403/06 A61K31/404 A61P9/06 A61P23/02

Abstract RU 2408579 C2

FIELD: chemistry.

SUBSTANCE: invention relates to novel indole derivatives, specifically to hydrogen halides of N-[2-(1-alkyl-1H-indol-3-yl)-1-(4-alkylpiperazine-1-carbonyl)-vinyl]-2-fluorobenzamide of formula I: , where R¹ and R²=alkyl C₁-C₆, X=Cl, Br, having local anaesthetic and antiarhythmic activity.

EFFECT: obtaining new indole derivatives having useful biological properties.

11 tbl, 1 ex

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RU 2 408 579 C2

Authors

Suzdalev Konstantin Filippovich

Babakova Marija Nikolaevna

Galenko-Jaroshevskij Pavel Aleksandrovich

Varlashkina Inessa Aleksandrovna

Cherednik Irina Leonidovna

Shejkh-Zade Jurij Reshadovich

Taran Oksana Anatol'Evna

Takhchidi Khristo Periklovich

Sakhnov Sergej Nikolaevich

Dol'Skaja Oksana Aleksandrovna

Lisitsyna Nadezhda Pavlovna

Bguasheva Behlla Askerovna

Bogus Saida Kazbekovna

Dates

2011-01-10—Published

2008-12-31—Filed