DNA-PK INHIBITORS Russian patent published in 2011 - IPC C07D409/14 A61P35/00 

Abstract RU 2408596 C2

FIELD: chemistry.

SUBSTANCE: invention describes a compound of formula I: and salts thereof, where R1 and R2 together with a nitrogen atom with which they are bonded can form a morpholine group; Q denotes -NH-C(=O)- or -O-; Y denotes a saturated aliphatic group C1-5alkylene group; X is selected from SR3 or NR4R5, where R3 denotes triazolyl; R4 and R5 are described in the claim.

EFFECT: compounds are DNA-PK inhibitors.

5 cl, 6 ex

Similar patents RU2408596C2

Title Year Author Number
NUCLEOSIDE ARYL PHOSPHORAMIDATES AND USE THEREOF AS ANTI-VIRAL AGENTS FOR TREATING HEPATITUS C VIRUS 2007
  • Mak Gajgehn Kristofer
  • Perroneh Plinio
RU2464272C2
PYRIMIDO[5,4-B]INDOLIZINE OR PYRIMIDO[5,4-B]PYRROLIZINE COMPOUND, METHOD FOR PRODUCTION THEREOF AND USE THEREOF 2017
  • Chzhan, Ao
  • Din, Tszyan
  • Se, Khua
  • Sun, Tszylan
  • Syue, Yu
  • Tun, Lintszyan
  • Gen, Mejyu
RU2721774C1
NOVEL PYRAZOLE PYRIMIDINE DERIVATIVES 2017
  • Keler, Adeline
  • Velts, Klaudia
  • Berngen, Kirsten
  • Kulke, Daniel
  • Ilg, Tomas
  • Kebberling, Jokhannes
  • Khyubsh, Valter
  • Shvarts, Khans-Georg
  • Gergens, Ulrikh
  • Ebbingkhaus-Kintsher, Ulrikh
  • Khink, Majke
  • Nennshtil, Dirk
  • Raming, Klaus
  • Adamchevski, Martin
  • Bem, Klaudia
  • Gribenov, Nils
  • Zhuang, Vej
RU2769448C2
TETRAHYDROIMIDAZOPYRIDINE DERIVATIVES AS MODULATORS OF TNF ACTIVITY 2014
  • Dzhekson Viktoriya Elizabet
  • Kroplin Boris
  • Loue Martin Aleksander
  • Porter Dzhon Robert
RU2697090C1
HETEROCYCLIC COMPOUNDS AS PAD INHIBITORS 2018
  • Hallur Gurulingappa
  • Duraiswamy Athisayamani Jeyaraj
  • Purra Buchi Reddy
  • Rao N.V.S.K.
  • Rajagopal Sridharan
RU2764243C2
METHODS FOR PREPARING DERIVATIVES OF PIPERAZINE AND INTERMEDIATE SUBSTANCE 2003
  • Chan Anita Vaj-Jin
  • Fejgel'Son Gregg Brajan
  • Zeldis Dzhozef
  • Dzhirkovski Ivo
RU2314294C2
INHIBITORS, A METHOD OF THEIR PREPARATION AND USE 2019
  • Liao, Xuebin
RU2806033C2
METHOD FOR SYNTHESIS OF CHIRAL N-ARYLPIPERAZINES 2003
  • Fejgel'Son Gregg Brajan
  • Zeldis Dzhozef
  • Dzhirkovski Ivo
RU2315762C2
CINNAMOYL DERIVATIVES OF DIBENZOFURANONE OXIME WITH ANTICONVULSANT ACTIVITY 2023
  • Seredenin Sergej Borisovich
  • Mokrov Grigorij Vladimirovich
  • Voronina Tatyana Aleksandrovna
  • Litvinova Svetlana Aleksandrovna
  • Zhmurenko Lyudmila Aleksandrovna
  • Biryukova Valentina Evgenevna
  • Shangin Stanislav Vladimirovich
  • Grigorkevich Oksana Sergeevna
  • Gudasheva Tatyana Aleksandrovna
  • Vakhitova Yuliya Venerovna
RU2810250C1
BENZO[1,3]DIOXIN DERIVATIVES AND THEIR USE AS LPAR5 ANTAGONISTS 2013
  • Nazare Mark
  • Kotsian Detlef
  • Bossart Martin
  • Chekhtizkij Verngard
  • Efers Andreas
RU2647727C2

RU 2 408 596 C2

Authors

Smit Grim Kehmeron Mjurrehj

Martin Najehl Morrison Barr

Minir Kejt Ehllan

Khammerson Mark Dzhefri

Rigoreh Loran Zhan Martin

Griffin Rodzher Dzhon

Golding Bernard Tomas

N'Juehl Dehvid Richard

Kalvert Khilari Alan

Kertin Nikolja Dzhejn

Khardkasl Ajen Robert

Saravanan Kappusehmi

Dates

2011-01-10Published

2005-09-20Filed