LanA2 PEPTIDE ISOLATED FROM BACILLUS LICHENIFORMIS VK21 BACTERIA, HAVING ANTIMICROBIC ACTION Russian patent published in 2011 - IPC C07K14/195 

Abstract RU 2408604 C1

FIELD: chemistry.

SUBSTANCE: described is a peptide having antimicrobic action, which has general formula: , where OBu is a 2-oxobutyric acid residue, Abu is a 2-aminobutyric acid residue, Dha is a 2,3-didehydroanaline residue, Dhb is a 2,3-didehydroaminobutyric acid residue, where residues in the sequence are joined by amide bonds, residues Ala7 and Ala11, Ala19 and Ala23 are joined in pairs by thioester bonds to form two lanthionine (Lan) residues, Abu25 and Ala28, Abu29 and Ala32 are joined in pairs by thioester bonds to form two 3-methyllanthionine (MeLan) residues.

EFFECT: high antimicrobic action of the peptide.

4 dwg, 1 tbl, 6 ex

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Authors

Ovchinnikova Tat'Jana Vladimirovna

Arsen'Ev Aleksandr Sergeevich

Balandin Sergej Vladimirovich

Nurmukhamedova Ehlina Kurban-Alievna

Tagaev Andrej Azisovich

Temirov Jurij Vital'Evich

Finkina Ekaterina Ivanovna

Shenkarev Zakhar Olegovich

Jakimenko Zoja Aleksandrovna

Dates

2011-01-10Published

2009-10-27Filed