FIELD: chemistry.
SUBSTANCE: described is a peptide having antimicrobic action, which has general formula: , where OBu is a 2-oxobutyric acid residue, Abu is a 2-aminobutyric acid residue, Dha is a 2,3-didehydroanaline residue, Dhb is a 2,3-didehydroaminobutyric acid residue, where residues in the sequence are joined by amide bonds, residues Ala7 and Ala11, Ala19 and Ala23 are joined in pairs by thioester bonds to form two lanthionine (Lan) residues, Abu25 and Ala28, Abu29 and Ala32 are joined in pairs by thioester bonds to form two 3-methyllanthionine (MeLan) residues.
EFFECT: high antimicrobic action of the peptide.
4 dwg, 1 tbl, 6 ex
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Authors
Dates
2011-01-10—Published
2009-10-27—Filed