PREMERSACIDINE, PROMERSACIDINE, DNA (VARIANTS), VECTOR (VARIANTS), METHOD OF MERSACIDINE PREPARING Russian patent published in 2003 - IPC

Abstract RU 2198924 C2

FIELD: biotechnology, genetic engineering, molecular biology, antibiotics. SUBSTANCE: invention relates to peptide antibiotic mersacidine and its precursors premersacidine and promersacidine, DNA encoding thereof, vectors comprising these DNAs and method of genetic engineering used for preparing mature mersacidine. Mature mersacidine is used as peptide antibiotic against infection of foodstuffs with methicilline-resistant Staphylococcus aureus or for treatment of human and animals with infections caused by Staphylococcus aureus. Invention can be used also for preparing modified derivatives of mersacidine with shifted antibiotic spectrum or with distinguishing effectiveness. EFFECT: enhanced expression of mersacidine or its derivatives. 11 cl, 3 dwg

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RU 2 198 924 C2

Authors

Koller Klaus-Peter

Zal' Khans Georg

Birbaum Gabrile

Dates

2003-02-20Published

1995-09-11Filed