FIELD: medicine.
SUBSTANCE: invention represents a pharmaceutical composition containing bacteriophage (Sextaphage® (Pyobacteriophage Polyvalent)) or Bacteriophage Salmonellous groups A, B, C, D, E) dried up with excipients (methyl cellulose, lactose, calcium carbonate, calcium or magnesium stearate) in the form of gastric-resistant uncoated tablets, differing by the fact that the relation of parity bacteriophage to excipients makes 1:1 to 1.25:1, and the composition contains in addition - sorbite and sodium alginate. One tablet of weight 0.16-0.2 g contains bacteriophages with Appelman titre not less than 10-3, and the ingredients of the components are in a certain ratio, wt %.
EFFECT: higher gastric resistance of tablets and stabilisation of bacteriophages.
2 cl, 3 ex
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Authors
Dates
2011-01-27—Published
2009-06-19—Filed