SEXTAPHAGE (PYOBACTERIOPHAGE POLYVALENT) OR BACTERIOPHAGE SALMONELLOUS PHARMACEUTICAL COMPOSITION AND METHOD FOR PRODUCING THEREOF Russian patent published in 2011 - IPC A61K9/20 A61K35/74 A61K47/02 A61K47/06 A61P1/00 

Abstract RU 2410084 C1

FIELD: medicine.

SUBSTANCE: invention represents a pharmaceutical composition containing bacteriophage (Sextaphage® (Pyobacteriophage Polyvalent)) or Bacteriophage Salmonellous groups A, B, C, D, E) dried up with excipients (methyl cellulose, lactose, calcium carbonate, calcium or magnesium stearate) in the form of gastric-resistant uncoated tablets, differing by the fact that the relation of parity bacteriophage to excipients makes 1:1 to 1.25:1, and the composition contains in addition - sorbite and sodium alginate. One tablet of weight 0.16-0.2 g contains bacteriophages with Appelman titre not less than 10-3, and the ingredients of the components are in a certain ratio, wt %.

EFFECT: higher gastric resistance of tablets and stabilisation of bacteriophages.

2 cl, 3 ex

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RU 2 410 084 C1

Authors

Kovjazina Natal'Ja Anatol'Evna

Reshetnikov Viktor Ivanovich

Funkner Elena Viktorovna

Efimova Marina Georgievna

Shitova Ol'Ga Ivanovna

Dates

2011-01-27Published

2009-06-19Filed