FIELD: biotechnology, medicine.
SUBSTANCE: method for preparing polybacteriophage involves the combination to a single volume of bacteriophages obtained in culturing microorganisms and phages in casein-acidic medium with the content of total nitrogen 1.96 ± 0.10 mg/ml. Bacteriophages with the Appelman's titer 10-5, not less, are combined to obtain a single volume and the following sterilizing filtration through membranes with pores size 0.2 mcm is carried out. Invention provides simplifying a method, reducing time for technological cycle and enhancing the preparation quality. Invention can be used in manufacturing medicinal biological bacteriophage-base preparations.
EFFECT: improved preparing method.
4 cl, 2 tbl, 2 ex
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Authors
Dates
2005-02-27—Published
2002-05-06—Filed