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2 412 158

(13)

(51)

IPC

C07C237/04(2006-01-01)

C07C237/50(2006-01-01)

A61K31/167(2006-01-01)

A61P9/06(2006-01-01)

(21) (22)

Application

2009100629/04, 2009-01-11

(24)

Start date

2009-01-11

(22)

Actual filing date

2009-01-11

(45)

Published

2011-02-20

(72)

Inventor

Pantsurkin Vladimir IvanovichGashkova Oksana VladislavovnaRudakova Irina PavlovnaSyropjatov Boris JakovlevichVakhrin Mikhail Ivanovich

(73)

Holder

Gosudarstvennoe Obrazovatel'Noe Uchrezhdenie Vysshego Professional'Nogo Obrazovanija Gosudarstvennaja Farmatsevticheskaja Akademija Federal'Nogo Agentstva Po Zdravookhraneniju I Sotsial'Nomu Razvitiju" Vpo Pgfa Roszdrava)

2'-BROMANILIDE-3-N,N-DIETHYLAMINOPROPANOIC ACID NITRATE, 2'- BROMANILIDE-3-N,N,N-TRIETHYLAMINOPROPANOIC ACID IODIDE, EXHIBITING ANTIARYTHMIC ACTIVITY Russian patent published in 2011 - IPC C07C237/04 C07C237/50 A61K31/167 A61P9/06

Abstract RU 2412158 C2

FIELD: chemistry.

SUBSTANCE: invention relates to 2'-bromanilide-3-N,N-diethylaminopropanoic acid nitrate (I)

and 2'-bromanilide-3-N,N,N-triethylaminopropanoic acid iodide (II)

having antiarythmic activity.

EFFECT: compounds have antiarythmic activity which surpasses that of lidocaine with virtually the same toxicity.

1 tbl, 1 ex

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RU 2 412 158 C2

Authors

Pantsurkin Vladimir Ivanovich

Gashkova Oksana Vladislavovna

Rudakova Irina Pavlovna

Syropjatov Boris Jakovlevich

Vakhrin Mikhail Ivanovich

Dates

2011-02-20—Published

2009-01-11—Filed