FIELD: chemistry.
SUBSTANCE: invention relates to a novel compound 4-methylanilide-N-n-propylpyrrolidine-2-carboxylic acid borate of formula:
, having anthelminthic activity. The compound is obtained through bromination of 5-chlorovaleric acid with subsequent conversion thereof into an acid chloride using thionyl chloride, further amination with 4-methylaniline and then ring closure with n-propylamine in 4-methylanilide-N-n-propylpyrrolidine-2-carboxylic acid and reaction of the latter with boric acid.
EFFECT: high activity of the compound.
1 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| 2'-BROMOANILIDE OF N-BUTYLPYRROLIDINE-2-CARBOXYLIC ACID HYDROCHLORIDE, HAVING ANTIARRHYTHMIC ACTIVITY | 2012 |
|
RU2504539C1 |
| 2,6-DIMETHYLANILIDE OF N-CYCLOHEXYLPYRROLIDINE-2-CARBOXYLIC ACID HYDROCHLORIDE, HAVING SURFACE, INFILTRATION AND CONDUCTION ANAESTHESIA ACTIVITY | 2012 |
|
RU2504538C2 |
| 2-METHYLANILIDE MORPHOLINOETHANOIC ACID SALICYLATE WITH ANTIARHYTHMIC ACTIVITY | 2008 |
|
RU2381220C2 |
| AMIDE OF 2-(3-METHYL-6-METHOXY-7-ETHOXY-3,4-DIHYDROISOQUINOLYL-1)-ETHANOIC ACID HYDROCHLORIDE, HAVING ANTHELMINTIC ACTIVITY | 2013 |
|
RU2543374C2 |
| HYPOTENSIVE N-2-(2'-METHYLPHENOXY)-ETHYLMORPHOLINE HYDROCHLORIDE | 2007 |
|
RU2354652C2 |
| 2'-BROMANILIDE-3-N,N-DIETHYLAMINOPROPANOIC ACID NITRATE, 2'- BROMANILIDE-3-N,N,N-TRIETHYLAMINOPROPANOIC ACID IODIDE, EXHIBITING ANTIARYTHMIC ACTIVITY | 2009 |
|
RU2412158C2 |
| N-ISOPROPYLAMIDE 2-(6,7-DIMETHOXY-3-SPIRO-CYCLOPENTYL-3,4-DIHYDROISOQUINOLYL-1)-ETHANOIC ACID HYDROCHLORIDE, WHICH POSSESSES HYPERTENSIVE ACTIVITY | 2010 |
|
RU2491277C2 |
| ANALGESIC AGENT | 2010 |
|
RU2447059C2 |
| N-(2-METHYLPHENOXYETHYL)-N-CYCLOHEXYLAMINE HYDROCHLORIDE POSSESSING HYPOTENSIVE ACTIVITY | 2005 |
|
RU2303026C1 |
| N-(2-FURANOYL)-5-IODOANTHRANYLIC ACID BENZYLAMIDE AND N-(2-FURANOYL)-5-IODOANTHRANYLIC ACID DIMETHYLAMIDE APPLICATION AS ANTIPHLOGISTIC MEDICINES | 2006 |
|
RU2337101C1 |
