METHOD FOR PREPARING DRUG FOR PROSTATE FUNCTION RECOVERY Russian patent published in 2011 - IPC A61K35/48 

FIELD: medicine.

SUBSTANCE: invention refers to technology of biologically active agents (BAA) of animal origin. A method for preparing a BAA for prostate function recovery involves grinding bull and/or puberty bull-calf prostate tissue, homogenising the intermediate product, keeping the homogenate in 3% aqueous solution of acetic acid and zinc chloride (ZnCl₂), separating water-soluble components of animal tissue cells by centrifugation to produce a supernatant to be concentrated, purified by ultrafiltration, adding glycine to the solution, sterilising and drying an end product. The solution of acetic acid is prepared of apyrogenic water; the homogenate is kept in the solution of acetic acid and zinc chloride at temperature 3-7°C for 48 h in being agitated by 0.5 portions every 4 h. The ultrafiltration process is executed in a circulation mode through a flat-chamber membrane installation with membrane filters of characteristic pore size d=300 A at temperature T≤10°C to produce a solution to be concentrated with the use of nano-filter compositional membranes. It enables to prepare an end product concentrate containing mixed ingredients of molecular weight M=5÷20.0 kDa to be dried by means of a spray-type drier.

EFFECT: method allows producing a high-yield powered therapeutically effective agent containing water-soluble ingredients of M<20,0 kDa.

4 cl, 1 ex, 2 dwg