FIELD: medicine, pharmacy.
SUBSTANCE: invention relates to drugs and concerns sustained-release oral compositions. Agent comprises micelle-forming water-soluble main drug showing a positive charge at physiological pH value, polymer showing an opposite charge chosen from group consisting of polyacrylic acid, carboxymethylcellulose, xanthane gum, hellane gum, guara gum, dextran-sulfate and carragheenan, polyethylene oxide and if necessary a hydrophilic base. Also, invention proposes a method for sustained-release of micelle-forming drug.
EFFECT: improved and valuable medicinal and pharmaceutical properties of agent.
20 cl, 4 tbl, 24 dwg, 13 ex
Title | Year | Author | Number |
---|---|---|---|
PHARMACEUTICAL COMPOSITION | 2002 |
|
RU2323006C2 |
BAB TRIBLOCK POLYMERS HAVING IMPROVED RELEASE CHARACTERISTICS | 2010 |
|
RU2575844C2 |
TABLETS OF TAMSULOSIN WITH MODIFIED RELEASE | 2002 |
|
RU2335280C2 |
PREORAL DELIVERY SYSTEM FOR PROTEIN SUBSTANCE (OPTIONS), PROTECTIVE COATING FOR DELIVERY SYSTEM (OPTIONS) | 2014 |
|
RU2665367C2 |
HYDROGEL PREPARATION EXHIBITING THE SUSTAINED DRUG RELEASE | 1993 |
|
RU2121830C1 |
CONTROLLED RELEASE TRIMETAZIDINE MATRIX TABLET | 2006 |
|
RU2367438C2 |
NEW DOSAGE FORM OF ECHINOCHROME A, A METHOD OF ITS PREPARATION AND USE | 2022 |
|
RU2800382C1 |
OXIDATION STABLE AND BREAKING RESISTANCE DOSAGE FORM | 2010 |
|
RU2567723C2 |
METHOD FOR PREPARING BIOADHESIVE COMPACTED MATRIXES WHICH MAY BE USED AS SUCH OR FOR PROLONGED RELEASE OF ACTIVE SUBSTANCES, AND COMPACTED MATRIXES PREPARED BY THIS METHOD | 2009 |
|
RU2519224C2 |
TIME-RELEASE PHARMACEUTICAL COMPOSITION AND USE THEREOF | 2003 |
|
RU2474416C2 |
Authors
Dates
2008-04-20—Published
2002-11-12—Filed