METHOD FOR DETERMINING INDICATIONS FOR DIPHTHERIA PROPHYLACTIC IMMUNISATION Russian patent published in 2011 - IPC G01N33/53 

FIELD: medicine.

SUBSTANCE: offered is a method for selection of a contingent indicated for diphtheria prophylactic immunisation: vaccination or revaccination. Venous blood serum of a person being tested and a reference venous blood serum sample are examined for levels of specific IgG to diphtheria antitoxin, IgG^T _DA and IgG^R _DA respectively. Saliva of the person being tested and a reference saliva sample are examined for levels of specific secretory IgA to diphtheria dialysate antigen, slgA^T _DDA and slgA^R _DDA respectively. The derived values slgA^T _DDA and slgA^R _DDA are compared, and the produced values are also compared thereby. Provided IgG^T _DA≤IgG^R _DA and slgA^T _DDA≤slgA^R _DDA, diphtheria prophylactic immunisation is considered to be indicated.

EFFECT: method presents more reliable determination of indications for diphtheria prophylactic immunisation.