FIELD: chemistry.
SUBSTANCE: invention relates to novel derivatives of isothiazole-3(2H)-OH-1,1-dioxides of formula (I) or pharmaceutically acceptable salts thereof, which can increase expression of LXR α and/or β, a pharmaceutical composition based on said derivatives, use thereof in preparing a medicinal agent, as well as novel intermediate compounds of formula (V) or salts thereof. In formulae 
(I), 
(V) R2 denotes phenyl, and R1 and R3 are as described in the claim.
EFFECT: improved properties of the derivatives.
7 cl, 9 dwg, 172 ex
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