COMPOUND CONTAINING N-HETEROARYL RESIDUE BOUND WITH CONDENSED CYCLIC RESIDUES FOR NAD(P)H-OXIDASE INHIBITION AND THROMBOCYTE ACTIVATION Russian patent published in 2011 - IPC C07D487/04 A61K31/519 A61P9/10 

FIELD: medicine, pharmaceutics.

SUBSTANCE: described are new compounds of general formula (I): het-X-AB (I) where het is pentamerous N-heteroaryl, additionally containing one O, S or N atom as a heteroatom with heteroaryl with additional O atom being condensed with a benzene ring, or hexamerous N-heteroaryl; X means S; and where N-atom of N- heteroaryl residue and an X group are separated by one carbon atom; AB means 1,2,3-triazolo[4,5-d] pyrimidine-7-yl radical of general formula (II): where R₃ is C_1-8alkyl, phenyl, benzyl optionally substituted; R₅-H, C_1-8alkyl or phenyl.

EFFECT: production of new compounds for preparing a pharmaceutical composition either effective for treating cardiovascular, cancer, autoimmune diseases, stroke, neurodegenerative diseases, cystic fibrosis, or used in antithrombotic therapy.

9 cl, 11 ex, 3 tbl