COMPOSITION WHICH CONTAINS VIRUS-LIKE PARTICLE (VLP) AND AMYLOID-BETA PEPTIDE Russian patent published in 2011 - IPC A61K39/385 A61K47/48 C07K16/18 A61P25/28 

Abstract RU 2415677 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to field of medicine and deals with composition, which contains virus-like particle (VLP) and amyloid-beta peptide. Substance of invention includes application of construction, which consists of virus-like particle (VLP) structure, which is chemically stitched with fragment of Aβ-1-42 peptide and its pharmaceutically acceptable salt for preparation of pharmaceutical composition, intended for treatment of dementia in patient by introduction of construction in dose 5-1000 mcg subcutaneously, every 4-8 weeks. Invention also includes combination, which includes construction on item 1, and at least, one agent, selected from group of medications, traditionally applied for treatment of Alzheimer's disease.

EFFECT: reduction of side effects.

16 cl, 6 ex

Similar patents RU2415677C2

Title Year Author Number
COMPOSITION CONTAINING AMYLOIDAL PEPTIDE Aβ-1-6 ATTACHED TO VIRUS-LIKE PARTICLE AND ADJUVANT 2011
  • Peter Ulrikh
  • Katja Baer
  • Zhorzh Imber
  • Mari-Zhoze Khellinger
  • Mari-Emmanjuel River
  • Ana Graf
RU2603486C2
METHOD OF USE IN THERAPY 2010
  • Andrea Pfajfer
  • Andreas Mus
  • Marija Pilgren
RU2579659C2
THERAPEUTIC VACCINE 2006
  • Pfajfer Andrea
  • Nikolo Klod
RU2440824C2
ACTIVE IMMUNISATION FOR CREATING SOLUBLE A-BETA ANTIBODIES 2004
  • Jednok Tehd
  • Vehskez Niki
  • S'Jubert Piter A.
RU2390350C2
PEPTIDE VACCINE FOR PREVENTION AND IMMUNOTHERAPY OF DEMENTIA OF THE ALZHEIMER'S TYPE 2013
  • Van Chan I
RU2696566C2
PREVENTION AND TREATMENT OF CEREBRAL AMYLOID ANGIOPATHY 2008
  • Shreter Salli
  • Gejms Kejt Dora
RU2523894C2
ANTI-AMYLOID BETA (A BETA) 1-42 MONOCLONAL ANTIBODIES POSSESSING THERAPEUTIC PROPERTIES 2006
  • Rut Greferat
  • Dejvid Khikman
  • Andreas Mus
  • Andrea Pfajfer
  • Klod Nikolo
RU2551782C2
COPPER AGONIST THAT BINDS WITH COPPER BINDING SITE OF AMYLOID PROTEIN-PRECURSOR (APP) AND/OR EXERTS INHIBITORY EFFECT ON RELEASE OF AMYLOID Aβ-PEPTIDE 2000
  • Bejrojter Konrad
  • Mul'Tkhaup Gerd
RU2236235C2
METHODS OF TREATING ALZHEIMER'S DISEASE 2015
  • Graham Robert
RU2720468C2
PEPTIDE VACCINE FOR PREVENTION AND IMMUNOTHERAPY OF ALZHEIMER-TYPE DEMENTIA 2013
  • Wang, Chang Yi
RU2811687C2

RU 2 415 677 C2

Authors

Graf Ana

Shtaufenbil' Mattias

Blehttler Tomas

Paganetti Raolo

Dates

2011-04-10Published

2005-11-03Filed