HETEROCYCLYLAMIDOSUBSTITUTED IMIDAZOLE DERIVATIVES Russian patent published in 2011 - IPC C07D401/12 C07D233/90 A61K31/4178 A61K31/4164 A61P31/12 

FIELD: medicine, pharmaceutics.

SUBSTANCE: present invention refers to heterocyclylsubstituted imidazole derivatives of general formula or to its pharmaceutically acceptable salts wherein R¹ stands for a group of formula where * stands for a position whereon a carbonyl group is bound, R⁴ stands for phenyl or pyridyl, and phenyl or pyridyl can be substituted by one substitute where the substitute is chosen from a group including haloid, nitrogroup, cyanogroup, trifluoromethyl, (C₁-C₆)alkyl and (C₁-C₆)alkoxygroup, R⁶ and R⁷ stands for hydrogen, R² stands for (C₁-C₆)alkyl, and alkyl can be substituted by a substitute where the substitute is chosen from a group including (C₃-C₆)cycloalkyl and (C₆)aryl where aryl can be substituted by a trifluoromethyl substitute, R³ stands for phenyl, and phenyl can be substituted by substitutes in number 1 to 2 independently chosen from a group including haloid, trifluoromethyl, trifluoromethoxygroup, difluoromethoxygroup, trifluoromethylthiogroup and (C₁-C₆)alkyl. Also, the invention refers to methods for producing compounds of formula I, to a drug prepared of the compound of formula I, to applying the compound of formula I for preparing the drug and to a method of controlling cytomegalovirus infection.

EFFECT: production of new imidazole derivatives exhibiting antiviral activity, particularly in relation to cytomegaloviruses.

10 cl, 4 tbl, 31 ex