HETEROCYCLYLAMIDE-SUBSTITUTED THAIZOLES, PYRROLES AND THIOPHENES Russian patent published in 2011 - IPC C07D401/14 C07D409/14 C07D417/14 A61K31/4965 A61P31/22 

FIELD: chemistry.

SUBSTANCE: compound of formula (I) has antiviral activity toward the human cytomegalovirus (HCMV) or some other representative of the Herpes virida group. In formula (I)

, R¹ is a group of formula , where * denotes the point of bonding to a carbonyl group, R³ denotes a pyridyl which can be substituted with a substitute independently selected from a group comprising C₁-C₆alkyl or a cyano group, R⁵ and R⁶ independently denote hydrogen, R² denotes a phenyl which can be substituted with a substitute selected from a group comprising a trifluoromethoxy group, a difluoromethoxy group and a monofluoromethoxy group, A is a group of formula

or , where * denotes the point of bonding to the carbonyl group, # denotes the point of bonding to the nitrogen atom of urea, R⁷ denotes C₁-C₆alkyl which can be substituted with a substitute selected from a group comprising C₃-C₆cycloalkyl, R⁸ and R⁹ independently denote hydrogen, halogen or C₁-C₆alkyl. The invention also relates to a method of producing a compound of formula (I) from a compound of formula , a method of producing a compound of formula (V), a medicinal agent containing the disclosed compound, use of the compound in preparing a medicinal agent and a method of fighting viral infections, among them human cytomegalovirus (HCMV) or some other representative of the Herpes viridae group.

EFFECT: high antiviral activity.

9 cl, 1 tbl, 39 ex