COMPOUNDS FOR INHIBITING 5-HYDROXYTRYPTAMINE AND NOREPINEPHRINE REUPTAKE OR FOR TREATING DEPRESSION, SYNTHESIS AND APPLICATION METHODS THEREOF Russian patent published in 2011 - IPC C07C219/24 C07C219/28 C07C271/44 A61K31/135 A61K31/222 A61K31/27 A61P25/00 

Abstract RU 2416598 C2

FIELD: chemistry.

SUBSTANCE: invention relates to novel compounds of formula (I), optical isomers or pharmaceutically acceptable salts thereof which can be used to inhibit or block reuptake of 5-hydroxytryptamine (5HT) and/or norepinephrine (NA), as well as for treating diseases associated with the central nervous system, a pharmaceutical composition based on said compounds and use thereof in preparing a medicinal agent. (I), where the chiral centre (*) can be R or S or RS (racemic mixture), R3 and R4 are independently selected from saturated alkyl, having 1-6 carbon atoms, and R1 and R2 are as described in the formula of invention.

EFFECT: high effectiveness of the compounds.

12 cl, 10 tbl, 3 dwg, 15 ex

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RU 2 416 598 C2

Authors

Chzhan Lupin

Dates

2011-04-20Published

2006-06-16Filed