FIELD: chemistry.
SUBSTANCE: invention relates to (3-trifluromethylphenyl)amide 6-(6-hydroxymethylpyrimidin-4-yloxy)naphthalene-1-carboxylic acid or tautomer or salt thereof. The invention also relates to a pharmaceutical composition which has protein kinase inhibiting activity, based on the said compound and use of the said compound to prepare pharmaceutical compositions for use in treating protein kinase dependent diseases, preferably proliferative diseases, particularly tumorous diseases.
EFFECT: improved properties of compounds.
6 cl, 115 ex
| Title | Year | Author | Number |
|---|---|---|---|
| BICYCLIC AMIDES AS KINASE INHIBITORS | 2005 |
|
RU2448103C2 |
| COMPOUNDS AND COMPOSITIONS AS PROTEINKINASE INHIBITORS | 2006 |
|
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| COMBINATION, INCLUDING A) PYRIMIDYLAMINOBENZAMIDE AND B) KINASE Thr315lle INHIBITOR | 2007 |
|
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| NOVEL PYRIMIDINE AMIDE DERIVATIVES AND USE THEREOF | 2003 |
|
RU2378267C2 |
| COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | 2006 |
|
RU2383545C2 |
| COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | 2006 |
|
RU2387653C2 |
| COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | 2006 |
|
RU2368602C2 |
| COMBINATIONS CONTAININS Bcr-Abl/c-Kit/PDGF-RTK INHIBITORS FOR TREATING CANCER | 2007 |
|
RU2452492C2 |
| ANTHRANILIC ACID AMIDES AND THEIR USING IN PHARMACEUTICALS | 2002 |
|
RU2315756C2 |
| ANTHRANILIC ACID AMIDES, METHOD FOR THEIR PREPARING AND THEIR USING, METHOD FOR TREATMENT OF NEOPLASM DISEASE AMD PHARMACEUTICAL DRUG POSSESSING INHIBITORY ACTIVITY WITH RESPECT TO TYROSINE KINASE VEGF RECEPTOR | 2002 |
|
RU2318811C2 |
