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(19)

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2 448 103

(13)

(51)

IPC

C07D403/12(2006-01-01)

C07D413/12(2006-01-01)

C07D239/47(2006-01-01)

C07D401/12(2006-01-01)

A61K31/505(2006-01-01)

A61K31/506(2006-01-01)

A61K31/4725(2006-01-01)

A61K31/5377(2006-01-01)

A61P35/00(2006-01-01)

(21) (22)

Application

2010138639/04, 2005-09-14

(24)

Start date

2005-09-14

(22)

Actual filing date

2005-09-14

(45)

Published

2012-04-20

(72)

Inventor

Bol'D GuidoKapraro Khans-GeorgKaravatti DzhordzhoFlerskhajmer AndreasFjure Paskal'Manli Pol U.Faupel' AndreaPisso-Zol'Dermann Karol'Zhess'E FransuaShnell' KristianLittlvud-Ehvans Amanda DzhejnKapa Prasad KotesvaraBajva Dzhoginder S.Tszjan Sinlon

(73)

Holder

Novartis Ag

BICYCLIC AMIDES AS KINASE INHIBITORS Russian patent published in 2012 - IPC C07D403/12 C07D413/12 C07D239/47 C07D401/12 A61K31/505 A61K31/506 A61K31/4725 A61K31/5377 A61P35/00

Abstract RU 2448103 C2

FIELD: chemistry.

SUBSTANCE: invention relates to specific derivatives of bicyclic amides disclosed in the claim, as well as a pharmaceutical composition.

EFFECT: compounds having protein kinase inhibiting activity, meant for use in treating protein kinase-dependant diseases, preferably proliferative diseases such as tumorous diseases.

13 cl, 115 ex

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RU 2 448 103 C2

Authors

Bol'D Guido

Kapraro Khans-Georg

Karavatti Dzhordzho

Flerskhajmer Andreas

Fjure Paskal'

Manli Pol U.

Faupel' Andrea

Pisso-Zol'Dermann Karol'

Zhess'E Fransua

Shnell' Kristian

Littlvud-Ehvans Amanda Dzhejn

Kapa Prasad Kotesvara

Bajva Dzhoginder S.

Tszjan Sinlon

Dates

2012-04-20—Published

2005-09-14—Filed