AZOLE COMPOUNDS WITH NEUTROTHERAPEUTIC ACTIVITY Russian patent published in 2011 - IPC C07D257/04 C07D403/12 C07D403/14 A61K31/4192 A61K31/41 A61P25/08 

Abstract RU 2418792 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: described are novel azole compounds, which contain carbamoyl group, of general formula IX: where A stands for azole group of general structural formula or G stands for ring, selected from group, consisting of piperonyl, indanyl, naphtyl, possibly substituted phenyl, benzodioxole and phenoxymethyl, (values of radicals are given in the invention formula), their pharmaceutically acceptable salts and pharmaceutical compositions, containing them, which can be applied for treatment of various central nervous system disorders, especially such as anxiety, depression, convulsions, epilepsy, migraine, bipolar disorder, medication abuse, smoking, ADHD, obesity, sleep disorder, neurogenic pain, stroke, cognitive impairment, neurodegeneration and muscle spasm.

EFFECT: obtaining novel azole compounds and their pharmaceutically acceptable salts and pharmaceutical compositions, containing them, which can be applied for treatment of various central nervous system disorders.

71 cl, 3 tbl, 199 ex

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Authors

Choi Eng-Mun

Kim Chun-Gil

Kang Jang-San

Ji Khan-Dzhu

Li Khian-Seok

Ku Bon-Chul

Li Jun-Kho

Im Dae-Dzhung

Shin Ju-Dzhin

Dates

2011-05-20Published

2006-04-21Filed