DERIVATIVES OF N-UREA-SUBSTITUTED AMINOACIDS AS MODULATORS OF FORMYL-PEPTIDE RECEPTOR Russian patent published in 2019 - IPC C07C275/28 C07C275/30 A61K31/17 A61P27/02 A61P29/00 

Abstract RU 2696581 C2

FIELD: chemistry.

SUBSTANCE: invention relates to a compound of formula I, its enantiomers, diastereomers or pharmaceutically acceptable salts which have the action of a modulator of N-formyl-peptide receptor 2. In formula IR1 is halogen or -CF3; R2 is C1-8 alkyl; R3 is H; R4 is C1-8 alkyl; R5 is H; R6 represents H; R7 is H or C1-8 alkyl.

formula I.

EFFECT: invention also relates to a pharmaceutical composition containing said compounds and use thereof for treating an eye inflammatory disease associated with modulating N-formyl-peptide receptor 2.

12 cl, 3 tbl, 2 ex

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RU 2 696 581 C2

Authors

Bird Richard L.

Duong Ten T.

Donello Dzhon E.

Visvanat Vina

Garst Majkl E.

Dates

2019-08-05Published

2014-07-10Filed