TAXOL DERIVATIVES WITH ANTICANCER ACTIVITY Russian patent published in 2011 - IPC C07D493/08 A61K31/357 A61P35/00 

Abstract RU 2419622 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to new compounds of formula (I) or to their salts:

,

where: R1 or R2, independently represents a group consisting of R1, R2, N and/or O selected from the groups:

,

Z1 represents hydrogen or hydroxyl; Z2 represents hydrogen or hydroxyl; Z3 represents C6-C10aryl; Z4 represents C1-C6alkoxy. The invention also refers to a method for producing the compounds according to any of claims 1-4, as well as to application of the compounds.

EFFECT: preparation of new biologically active compounds which exhibit anticancer activity.

12 cl, 10 ex, 3 tbl, 2 dwg

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RU 2 419 622 C2

Authors

Sun' Pjaojan

Lehj Sin'Shehn

Juan' Kajkhun

Dates

2011-05-27Published

2007-01-05Filed