FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to new compounds of formula (I) or to their salts:
,
where: R1 or R2, independently represents a group consisting of R1, R2, N and/or O selected from the groups:
,
Z1 represents hydrogen or hydroxyl; Z2 represents hydrogen or hydroxyl; Z3 represents C6-C10aryl; Z4 represents C1-C6alkoxy. The invention also refers to a method for producing the compounds according to any of claims 1-4, as well as to application of the compounds.
EFFECT: preparation of new biologically active compounds which exhibit anticancer activity.
12 cl, 10 ex, 3 tbl, 2 dwg
| Title |
Year |
Author |
Number |
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|
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|
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|
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|
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|
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|
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|
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- Rouz Vil'Jam S.
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|
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