FIELD: medicine, pharmaceutics.
SUBSTANCE: present invention refers to compounds of formula
, as well as to application of such compounds for preparing a drug which is administered for treatment, relief or prevention of a condition associated with canal activating protease, such as prostasin or trypsin.
-J-(R10)p = 
or 
.
EFFECT: preparing the pharmaceutical compositions which exhibit prostasin or trypsin inhibiting activity.
13 cl, 2 tbl, 53 ex
| Title | Year | Author | Number |
|---|---|---|---|
| 1,2,4-TRIAZINE-6-ONE DERIVATIVES, INHIBITING HIV | 2005 |
|
RU2401833C2 |
| PYRIMIDINE SUBSTITUTED MACROCYCLIC HCV INHIBITORS | 2008 |
|
RU2481340C2 |
| REVERSE TRANSCRIPTASE NUCLEOSIDE INHIBITORS | 2007 |
|
RU2451676C2 |
| MACROCYCLIC PHENYLCARBAMATES INHIBITING HCV | 2008 |
|
RU2490261C2 |
| NEW COMPOUNDS | 2013 |
|
RU2654857C2 |
| ANTI-CANCER BENZOPYRAZINES ACTING THROUGH FGFR-KINASES INHIBITION | 2012 |
|
RU2639863C2 |
| PEPTIDE EPOXY KETONES FOR PROTEASOME INHIBITION | 2007 |
|
RU2450016C2 |
| 1,5-BENZOTHIAZEPINES AND EMPLOYMENT THEREOF AS ANTIHYPERLIPIDEMIC DRUGS | 2001 |
|
RU2302414C2 |
| OXYSTEROLES AND METHODS OF USING THEM | 2016 |
|
RU2744267C2 |
| SUBSTITUTED DERIVATIVES OF N-PHENYL-2-HYDROXY-2-METHYL-3,3,3-TRIFLUOROPROPANEAMIDE ENHANCING ACTIVITY OF PYRUVATE DEHYDROGENASE | 2000 |
|
RU2255085C2 |
