REVERSE TRANSCRIPTASE NUCLEOSIDE INHIBITORS Russian patent published in 2012 - IPC C07D231/12 C07D231/56 C07D471/04 C07D487/04 C07D231/20 A61K31/415 A61K31/416 A61K31/437 A61K31/519 A61K31/4985 A61K31/5025 A61P31/18 

Abstract RU 2451676 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: this invention relates to compounds that may be applied for HIV infection treatment or prevention or for AIDS or AIDS-associated complex treatment. According to the invention, the compounds represent compounds with formula I, where A stands for A1 , A2 , A3 or A4 and R1, R2, R3, R4a, R4b, R5, R6, Ar, X1, X2, X4, X4 and X5 having values specified in the patent claim. Additionally, this invention relates to a pharmaceutical composition containing the said compounds.

EFFECT: production of compounds possessing inhibition activity with regard to HIV reverse transcriptase.

22 cl, 3 tbl, 29 ex

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RU 2 451 676 C2

Authors

Kennedi-Smit Dzhoshua

Palmer Uajli Solang

Suini Zakari Kevin

Dates

2012-05-27Published

2007-08-06Filed