HYDROPHYLIC GEL, METHOD OF ITS OBTAINING (VERSIONS), WOUND COVERING AND BASED ON IT BANDAGE MEANS Russian patent published in 2011 - IPC A61K9/00 A61L15/22 A61L15/28 A61F13/02 A61L15/44 

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to field of medicine, namely to bandage means, used for treatment of burns, trophic ulcers and other skin lesions, as well as to methods of their obtaining. Described is gel, representing sparsely-cross-linked chitosan and polyanionic hydrocolloid polymer, which has 2-3 linkages of copolymers per chitosan molecule, and distributed in it auxiliary substances. As polyanionic hydrocolloid, used is suspension of sucralfate or polyalginic acid particles, containing 0.01-15 wt % of stabiliser. As stabiliser used is highly molecular polyalcohols, such as polyvinyl alcohol, polyethylene glycol, as well as polyvinylpyrrolidone or silver microparticles. Auxiliary substances are introduced into gel individually or together in concentrations from 0.01 to 30% of gel dry weight. Gel is obtained by mixing chitosan with polyanionic hydrocolloid, into which preliminarily introduced were stabiliser and auxiliary substances. Bandage material represents hydrogel layer, applied on biocompatible film from water-insoluble polymer with pores with diameter D=(0.01-5.0) mcm. Covering can be on wounds during long term from 2 to 20 days and produce medicinal effect during said period.

EFFECT: bandage means can be used in treatment of trophic ulcers and various wound types, including wounds polluted with microorganisms, trophic wounds and prolonged non-healing wounds, and also be applied as allogen skin substitute in operations aimed at recovery of skin in patients with extensive burns.

16 cl, 11 ex