CHITIN DERIVATIVE ACTIVE POLYMER LAYER, IN PARTICULAR, FOR DRESSING AND APPLICATION THEREOF Russian patent published in 2019 - IPC A61L15/28 A61L15/42 A61L15/44 

FIELD: medicine.

SUBSTANCE: group of inventions relates to the field of medicine, namely to the variants of the active polymer layer for the wound dressing. In the first embodiment, the layer is obtained by the method, according to which the water-soluble pore-forming substance is distributed on a non-absorbing surface, which is then applied a solution of at least one derivative of chitin in an organic solvent when the mass ratio of the derivative(s) of chitin to the pore-forming substance is from 1/5 to 1/40, then the solvent is evaporated and washed with water. In another embodiment, the layer is obtained by the following method:at least one derivative of chitin at a concentration of 0.1–99 % is dissolved in a solution of LiCl with a concentration of 5–6 % in N, N-dimethylacetamide, CaCO₃ is added to the solution, the mixture is poured onto a non-absorbent surface, then the solvent is evaporated, washed with hydrochloric acid solution and water, dried. In both cases, a chitin derivative is obtained by esterification of chitin in the presence of unbranched saturated aliphatic anhydrides with a C2-C8 chain length, or methacrylic anhydride, or 2-butenoic anhydride, or maleic anhydride, or succinic anhydride, or phthalic anhydride.

EFFECT: group of inventions provides faster regeneration of the skin, as well as increased viability and cell adhesion.

23 cl, 14 dwg, 1 tbl, 17 ex