FIELD: medicine, pharmaceutics.
SUBSTANCE: invention relates to field of medicine. Phosphorilated 1-hydroperfluorisopropanols of formula 1 are applied as effective medication for irreversible inhibition in vivo of carboxylesterase. Said compounds represent (O,O-diethyl)-01-trifluormethyl-2,2,2-trifluorethylphosphate. In order to inhibit in vivo carboxylesterase in plasma of rodents, effective amount of said compounds is introduced to animals.
EFFECT: compounds have low acute toxicity and possess high therapeutic index.
7 cl, 2 dwg, 2 tbl, 3 ex
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