CYTOTOXIC T-CELL (CTC) INDUCING PEPTIDE, METHOD OF INDUCING CTC, ANTIBODY BOUND TO SAID PEPTIDE, USE OF SAID PEPTIDE IN PHARMACEUTICAL COMPOSITION AND FOR TREATING OR PREVENTING CANCER, ANTIGEN-PRESENTING CELL Russian patent published in 2011 - IPC C07K7/06 A61K38/08 A61P35/00 C07K16/34 C12N5/07 

FIELD: chemistry.

SUBSTANCE: invention relates to peptides which induce cytotoxic T-cells of general formula ,

where X is a tyrosine residue or methionine residue; each of Y and Z is a single bond; R¹ is a hydrogen atom; R² is a hydroxyl; R³ is hydrogen, amino, C_1-6alkylcarbonylamino substituted with 1-2 substitutes selected from a group comprising carboxy and amino; R⁴ is a carboxy or a group of formula , where W is an amino acid residue; m equals 1 and n equals an integer from 0 to 1, provided that when n equals 0, R³ is hydrogen; pharmaceutically acceptable salts thereof, and use thereof in cancer immunotherapy.

EFFECT: more effective use of the compounds.

17 cl, 9 dwg, 2 tbl, 7 ex