METHOD OF EVALUATING IMMUNOSUPPRESSIVE RESPONSE RATE IN CHILDREN WITH CHRONIC GLOMERULONEPHRITIS Russian patent published in 2011 - IPC G01N33/53 

Abstract RU 2425381 C1

FIELD: medicine.

SUBSTANCE: invention describes a method of evaluating an immunosuppressive response rate in children with chronic glomerulonephritis characterised by determining the peripheral blood cell kinetics by flow DNA-cytometry; evaluating a cell fraction in a proliferation phases not less than 0.74% enables to consider the immunosuppressive therapy to be prescribed, and observing a decreased cell level in proliferation phases in 2-3 weeks after the beginning of administration at least in 2 times, the therapy is considered to be effective; the absence of positive dynamics requires dosage change or preparation replacement.

EFFECT: higher accuracy and reduced number of research injures, derived clinical laboratory criteria of immunosuppressive prescription and prediction of a therapeutic effect.

4 dwg, 1 tbl, 3 ex

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RU 2 425 381 C1

Authors

Kal'Met'Eva Linara Rinatovna

Khajrullina Raisa Masgutovna

Khasanov Rinat Shajmullovich

Khasanova Asija Shajmullovna

Khisamova Nazilja Fagil'Evna

Sakaeva Farida Zufarovna

Dates

2011-07-27Published

2010-03-29Filed