FIELD: medicine.
SUBSTANCE: invention refers to medicine, namely to oncology, and can be used to determine the therapeutic approach to the patients with metastatic forms and recurrent triple-negative breast cancer (TNBC). Concentration of cells expressing markers CD36+CD163+CD206+, LIN-HLADR-CD33+CD66b-CD14+CD15- is determined in the tumour microenvelopment. Blood concentration of gamma/delta T-lymphocytes is determined. Level of spontaneous production of TNF-α and TGF-β is determined in lymphocyte culture. Derived values are used to calculate the discriminant functions F1, F2 and F3. Therapeutic approach is determined by the highest value of one of the functions.
EFFECT: method provides the effective determination of the therapeutic approach in the patients with metastatic forms and recurrent TNBC by creating an algorithm which enables to select the most effective method of treatment from alternative versions.
1 cl, 9 tbl
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