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2 425 874

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(51)

IPC

C12N5/18(2006-01-01)

C12P21/08(2006-01-01)

(21) (22)

Application

2010114795/10, 2010-04-13

(24)

Start date

2010-04-13

(22)

Actual filing date

2010-04-13

(45)

Published

2011-08-10

(72)

Inventor

Alekseeva Ljudmila PavlovnaEvdokimova Veronika VjacheslavovnaFateeva Oksana Fedorovna

(73)

Holder

Federal'Noe Gosudarstvennoe Uchrezhdenie Zdravookhranenija Ordena Trudovogo Krasnogo Znameni Nauchno-Issledovatel'Skij Protivochumnyj Institut" Federal'Noj Sluzhby Po Nadzoru V Sfere Zashchity Prav Potrebitelej I Blagopoluchija Cheloveka

CULTIVATED HYBRID CELL STRAIN OF Mus musculus L ANIMALS - PRODUCER OF MONOCLONAL ANTIBODIES SPECIFIC TO O-ANTIGENE OF CHOLERA VIBRIO SEROGROUP O1 Russian patent published in 2011 - IPC C12N5/18 C12P21/08

Abstract RU 2425874 C1

FIELD: medicine.

SUBSTANCE: invention can be used in creating diagnostic test systems of monoclonal antibodies (MCA-01) for accelerated identification of cholera vibrios serogroup O1 of serovars Ogawa and Inaba. The cultivated cell strain of mouse hybridoma is produced by conventional methods used in the monoclonal antibody technology. A cloning procedure results in preparing a productive strain stably producing monoclonal antibodies isotype JgG specific to O-antigen of cholera vibrios O1 serogroup. The strain is deposited in Specialised Collection of continuous somatic cells of the Vertebrata Institute of Cytology (St.-Petersburg), No. RKKK (P) 386D.

EFFECT: hybridoma produced MCA-01 actively reacts with O-antigen determinants of the strains of serovars Ogawa and Inaba and do not react with related microorganisms.

1 tbl, 3 ex

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RU 2 425 874 C1

Authors

Alekseeva Ljudmila Pavlovna

Evdokimova Veronika Vjacheslavovna

Fateeva Oksana Fedorovna

Dates

2011-08-10—Published

2010-04-13—Filed