Show metadata Hide metadata

(19)

(11)

2 425 875

(13)

(51)

IPC

C12N5/18(2006-01-01)

C12P21/08(2006-01-01)

G01N33/569(2006-01-01)

(21) (22)

Application

2010123205/10, 2010-06-07

(24)

Start date

2010-06-07

(22)

Actual filing date

2010-06-07

(45)

Published

2011-08-10

(72)

Inventor

Alekseeva Ljudmila PavlovnaMarkina Ol'Ga VladimirovnaFateeva Oksana FedorovnaJagovkin Mikhail Ehduardovich

(73)

Holder

Federal'Noe Gosudarstvennoe Uchrezhdenie Zdravookhranenija Ordena Trudovogo Krasnogo Znameni Nauchno-Issledovatel'Skij Protivochumnyj Institut" Federal'Noj Sluzhby Po Nadzoru V Sfere Zashchity Prav Potrebitelej I Blagopoluchija Cheloveka

CULTIVATED HYBRID CELL STRAIN OF Mus Musculus L ANIMALS - PRODUCER OF MONOCLONAL ANTIBODIES SPECIFIC TO LPS OF CHOLERA VIBRIO 0139 SEROGROUP Russian patent published in 2011 - IPC C12N5/18 C12P21/08 G01N33/569

Abstract RU 2425875 C1

FIELD: medicine.

SUBSTANCE: cultivated cell strain of Mus. musculus L animals that is a producer of monoclonal antibodies (MCA) specific to LPS of cholera vibrios 0139 serogroup is produced. Hybridoma is deposited in Specialised Collection of continuous somatic cells of the Vertebrata Institute of Cytology (St.-Petersburg), No. RKKK (P) 674D. The specific activity of the MCA produced by hybridoma under the invention as a diagnostic reagent is proved in a slide agglutination reaction. The produced hybridoma can be applied in creating diagnostic test systems of the monoclonal antibodies for accelerated identification of cholera vibrios O139 serogroup.

EFFECT: invention use allows producing the diagnostically significant monoclonal antibodies to LPS epitopes of cholera vibrios 0139 serogroup that allows higher effectiveness of laboratory cholera researches.

3 tbl, 4 ex

Similar patents RU2425875C1

Title	Year	Author	Number
CULTIVATED HYBRID CELL STRAIN OF Mus musculus L ANIMALS - PRODUCER OF MONOCLONAL ANTIBODIES SPECIFIC TO O-ANTIGENE OF CHOLERA VIBRIO SEROGROUP O1	2010	Alekseeva Ljudmila Pavlovna Evdokimova Veronika Vjacheslavovna Fateeva Oksana Fedorovna	RU2425874C1
STRAIN OF CULTURED ANIMAL HYBRID CELLS MUS. MUSCULUS - PRODUCER OF MONOCLONAL ANTIBODIES TO THE MEMBRANE PROTEIN COMMON TO TYPICAL AND ATYPICAL SEROGROUP 01 CHOLERA VIBRIOS	2022	Evdokimova Veronika Vyacheslavovna Alekseeva Lyudmila Pavlovna Yakusheva Olga Aleksandrovna Levchenko Darya Aleksandrovna Kruglikov Vladimir Dmitrievich	RU2785463C1
METHOD OF OBTAINING A MONOCLONAL PEROXIDASE CONJUGATE FOR THE IDENTIFICATION OF TYPICAL AND ATYPICAL STRAINS OF VIBRIO CHOLERAE O1, INCLUDING R-VARIANTS IN DOT-ELISA	2022	Alekseeva Lyudmila Pavlovna Evdokimova Veronika Vyacheslavovna Yakusheva Olga Aleksandrovna Levchenko Darya Aleksandrovna Kruglikov Vladimir Dmitrievich	RU2800470C1
STRAIN OF CULTIVATED ANIMAL HYBRID CELLS MUS MUSCULUS-PRODUCER OF MONOCLONAL ANTIBODY TO THE MEMBRANE PROTEIN, WHICH IS COMMON FOR TCP + THE STRAINS OF CHOLERA VIBRIOS OF THE O1 AND O139 SEROGROUPS	2017	Alekseeva Lyudmila Pavlovna Evdokimova Veronika Vyacheslavovna	RU2663003C1
METHOD OF DETECTING NON-CULTIVATED CULTURES OF Vibrio cholerae O1 AND O139 SEROUS-GROUPS AND PREDICTING THEIR POTENTIAL CAPABILITY TO REVERSION	2004	Sokolenko Anna Vasil'Evna	RU2287824C2
METHOD AND SET FOR DETERMINATION OF CHOLERA TOXIN PRODUCTION AND DIFFERENTIATION OF EPIDEMIOLOGICALLY SIGNIFICANT STRAINS OF CHOLERA VIBRIOS OF CLASSICAL AND EL TOR BIOVARS	2016	Mikheeva Elena Aleksandrovna Osina Nataliya Aleksandrovna Devdariani Zurab Levanovich Shcherbakova Svetlana Anatolevna Kutyrev Vladimir Viktorovich	RU2611359C1
SET OF BACTERIA STRAINS FOR TEACHING PROBLEMS OF MICROBIOLOGY AND METHODS OF LAB DIAGNOSIS OF CHOLERA	2019	Rastuntseva Elena Vasilevna Popov Yurij Alekseevich Tikhomirova Lyudmila Aleksandrovna Valova Tatyana Vladimirovna Gracheva Irina Vasilevna Chervyakova Nadezhda Sergeevna Osina Nataliya Aleksandrovna	RU2743454C1
COMPLEX GENE- AND IMMUNODIAGNOSTIC TEST-SYSTEM FOR IDENTIFICATION OF CHOLERA VIBRIONS OF O1 AND O139 SEROGROUPS AND ESTIMATION OF THEIR VIRULENCE	2009	Zadnova Svetlana Petrovna Livanova Ljudmila Fedorovna Krepostnova Irina Mikhajlovna Zakharova Tat'Jana L'Vovna Osin Aleksandr Vladimirovich Smirnova Nina Ivanovna	RU2404257C1
STRAIN OF HYBRIDOUS CULTURED MAMMALIAN CELLS MUS MUSCULIS L - A PRODUCER OF MONOCLONAL ANTIBODIES TO CHOLERIC ENTEROTOXIN OF ELTOR BIOTYPE	0	Slavyanskaya Tatyana Aleksandrovna Mareev Viktor Ivanovich Kirillova Elena Fedorovna Lesnykh Tatyana Mikhajlovna	SU1742325A1
HYBRID STRAIN OF CULTURED CELLS OF ANIMALS MUS MUSCULUS -T 2E5 - PRODUCER OF MONOCLONAL ANTIBODIES ISOTYPE G 1 TO B SUBUNIT OF CHOLERA TOXIN	2015	Mikheeva Elena Aleksandrovna Devdariani Zurab Levanovich Osina Natalija Aleksandrovna	RU2583306C1

RU 2 425 875 C1

Authors

Alekseeva Ljudmila Pavlovna

Markina Ol'Ga Vladimirovna

Fateeva Oksana Fedorovna

Jagovkin Mikhail Ehduardovich

Dates

2011-08-10—Published

2010-06-07—Filed