FIELD: medicine.
SUBSTANCE: group of the inventions relates to medicine and deals with method of determination of cholera toxin production and differentiation of epidemiologically significant strains of cholera vibrios, which includes preparation of tested sample, identification of cholera toxin by ELISA method, which provides introduction of antigens in holes of tablet, incubation and registration of results. Group of the inventions also deals with set for determination of cholera toxin production and differentiation of epidemiologically significant strains of cholera vibrios, realising claimed method.
EFFECT: group of the inventions ensures creation of highly specific, sensitive, simple and available for reproduction, without application of additional equipment, biologically safe, financially not costly (low cost price), executable for short amount of time method for determination of cholera toxin, produced by strains of cholera causative agent of classical and el tor biovars in conditions in vitro and in vivo, and differentiation of toxigenic (epidemiologically significant) strains of V cholerae.
4 cl, 3 ex, 3 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| TEST KIT FOR DETECTING CHOLERA TOXIN IN CULTIVATION MEDIUM | 2020 |
|
RU2737776C1 |
| CULTIVATED HYBRID ANIMAL CELLS MUS MUSCULUS HT 3E5 - PRODUCER OF MONOCLONAL ANTIBODIES ISOTYPE G 2A TO B- SUBUNIT OF CHOLERA TOXIN | 2015 |
|
RU2590587C1 |
| HYBRID STRAIN OF CULTURED CELLS OF ANIMALS MUS MUSCULUS -T 2E5 - PRODUCER OF MONOCLONAL ANTIBODIES ISOTYPE G 1 TO B SUBUNIT OF CHOLERA TOXIN | 2015 |
|
RU2583306C1 |
| COMPLEX GENE- AND IMMUNODIAGNOSTIC TEST-SYSTEM FOR IDENTIFICATION OF CHOLERA VIBRIONS OF O1 AND O139 SEROGROUPS AND ESTIMATION OF THEIR VIRULENCE | 2009 |
|
RU2404257C1 |
| STRAIN OF BACTERIA VIBRIO CHOLERAE - PRODUCER OF CHOLERAIC TOXIN OF II TYPE | 2007 |
|
RU2326941C1 |
| METHOD FOR IDENTIFYING TOXIGENIC V CHOLERAE O1 STRAINS, DETERMINING ITS BIOVAR AND DIFFERENTIATING BIOVAR ELTOR STRAINS BY TYPICAL AND CHANGED BY MULTIPLEX POLYMERASE CHAIN REACTION, AND TEST SYSTEM FOR IMPLEMENTATION THEREOF | 2011 |
|
RU2458141C1 |
| METHOD FOR IDENTIFICATION OF TOXIGENIC GENETIC VARIANTS OF CHOLERA CAUSATIVE AGENT EL TOR WITH SET OF MUTATIONS IN GENES OF VIRULENCE AND PANDEMIC ISLAND GENES BY MULTIPLEX POLYMERASE CHAIN REACTION | 2022 |
|
RU2815711C2 |
| METHOD OF PRODUCING CHOLERA TOXIN FOR CONTROL OF PRODUCTION OF CHOLERA CHEMICAL VACCINE | 2022 |
|
RU2799574C1 |
| METHOD DETECTION AND EVALUATION OF BIOTYPE, SEROGROUP AND TOXIGENICITY OF CHOLERA AGENT AND RELATED KIT | 2007 |
|
RU2360972C1 |
| AVIRULENT STRAIN OF Vibrio cholerae KM 263 BACTERIA OF SEROVAR INABA OF BIOVAR ELTOR - PRODUCER OF PROTECTIVE O1 ANTIGEN | 2010 |
|
RU2425867C1 |
