FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to molecular biology, immunology, virology and concerns a method of preparing a biologically active complex. A method is enabled by mixing an aqueous suspension of a modified rod-like virus particle with an aqueous solution of polypeptide. The modified virus particle is presented by a reaction product of 1 weight fraction of rod-like virus particle and 0.01-0.1 weight fractions of water-soluble polymer and cationic groups in an aqueous medium. 1 weight fraction of the modified rod-like virus particle is mixed with 0.1-25 weight fractions of polypeptide.
EFFECT: method can be used for preparing vaccine and therapeutic preparations for viral and other infectious diseases and other purposes.
3 tbl, 4 ex
| Title | Year | Author | Number |
|---|---|---|---|
| BIOLOGICALLY ACTIVE COMPLEX EXHIBITING INFLUENZA VIRUS PROTECTIVE ACTIVITY | 2009 |
|
RU2427385C1 |
| VACCINE PREPARATION | 2009 |
|
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| IMMUNOGENIC COMPOSITION, CONTAINING FOREIGN ANTIGENS ON SURFACE OF SPHERICAL CARRIERS, OBTAINED BY THERMAL DENATURATION OF SPIRAL VIRUSES | 2010 |
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|
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| VIRIONS AND VIRUS-LIKE PARTICLES OF ALTERNANTHERA MOSAIC VIRUS AS AMPLIFIERS OF IMMUNE RESPONSE | 2015 |
|
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| ANTIGEN FOR RECOMBINANT VACCINE AGAINST RUBELLA VIRUS | 2019 |
|
RU2709328C1 |
| BIOCIDAL COATING COMPOSITION | 2014 |
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| METHOD OF VIRUS QUANTITATIVE DETERMINATION | 1993 |
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RU2065497C1 |
